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Prema Health

Dermatology

Photodynamic Therapy (PDT)

PDT

About this treatment

Photodynamic Therapy (PDT) is an advanced dermatological treatment that combines a light-sensitive medication with targeted light therapy to treat pre-cancerous skin cells and certain skin conditions. At Prema Health in Portsmouth and Hampshire, our dermatologist-led team uses this proven technique to effectively target abnormal cells while preserving healthy surrounding tissue.

The treatment works by applying a photosensitising cream to the affected area, which is then absorbed by abnormal cells. After a specific incubation period, a special light is applied to activate the medication, destroying the targeted cells. This non-invasive approach is particularly effective for treating actinic keratoses, also known as solar keratoses, which are rough, scaly patches caused by sun damage that can potentially develop into skin cancer if left untreated.

PDT is performed by our experienced dermatology specialists at our Portsmouth clinic, serving patients across Hampshire including Gosport, Fareham, Cosham, and Havant. The 45-minute treatment session offers a safe and effective alternative to surgical procedures, with minimal downtime and excellent cosmetic outcomes. Our dermatologist-led approach ensures you receive expert care tailored to your specific skin concerns.

As part of our comprehensive Dermatology services, PDT represents one of the most advanced treatments available for managing pre-cancerous skin lesions. Many patients combine this treatment with regular Mole Checks to maintain optimal skin health and early detection of potential problems.

Duration

45 Mins

Key Benefit

Treats Pre-Cancerous Cells

Downtime

Minimal - 2-3 days

Results

Visible improvement within 2-4 weeks as treated skin heals

No Waiting Times No Waiting Times

In More Detail

Photodynamic Therapy at Prema Health follows a carefully structured protocol to ensure optimal results. During your appointment, our dermatologist will first cleanse the treatment area and apply a photosensitising agent, typically aminolevulinic acid (ALA) or methyl aminolevulinate (MAL). This cream is left on the skin for 1-3 hours to allow selective absorption by the abnormal cells. The light activation phase then takes approximately 10-20 minutes, during which a specific wavelength of light is directed at the treated area. Some patients experience a tingling or burning sensation during light exposure, which subsides once the treatment is complete.

Following your PDT treatment in Portsmouth or Hampshire, you can expect some redness, swelling, and sensitivity in the treated area for 2-3 days. The skin may develop a crusted appearance as abnormal cells are eliminated and the skin begins its natural healing process. It is essential to avoid direct sunlight for 48 hours after treatment and to use high-factor sun protection for several weeks following the procedure. Most patients require 1-2 treatment sessions for optimal results, though this will be determined during your consultation based on the extent and severity of the condition being treated.

Our dermatologist-led team provides comprehensive aftercare instructions and is available to address any concerns throughout your treatment journey. We serve patients from across Portsmouth, Gosport, Fareham, Cosham, Havant, and the wider Hampshire area, offering convenient appointment times and expert care in a comfortable clinical environment.

Frequently Asked Questions

1. Is PDT treatment painful?

Most patients experience a tingling, stinging, or burning sensation during the light activation phase of PDT treatment. This discomfort is generally tolerable and subsides immediately once the light is switched off. Some areas of the body may be more sensitive than others. Our dermatology team can discuss pain management options during your consultation if you have concerns about discomfort.

2. How many PDT sessions will I need?

The number of sessions required depends on the condition being treated and its severity. Most patients achieve excellent results with 1-2 treatment sessions spaced 4-8 weeks apart. During your initial consultation at our Portsmouth clinic, our dermatologist will assess your skin and recommend a personalised treatment plan. Some patients may benefit from annual maintenance treatments to prevent recurrence of pre-cancerous lesions.

3. What should I avoid after PDT treatment?

For 48 hours following your PDT treatment, you must avoid direct sunlight and bright indoor lighting as your skin will be extremely photosensitive. Do not use sunbeds, and avoid hot water, strenuous exercise, and alcohol for 24-48 hours. After the initial 48-hour period, use a high-factor broad-spectrum sunscreen (SPF 50+) and protect treated areas from sun exposure for at least 2 weeks. Our team will provide detailed aftercare instructions specific to your treatment.

4. Can PDT treat skin cancer?

PDT is primarily used to treat pre-cancerous skin lesions such as actinic keratoses, which helps prevent the development of skin cancer. It can also treat certain superficial forms of non-melanoma skin cancer in specific cases. However, it is not suitable for all types of skin cancer. Our dermatologist will conduct a thorough assessment and may refer you for a biopsy if necessary to determine the most appropriate treatment for your individual situation.

5. Are there any side effects of PDT?

Common side effects include redness, swelling, crusting, and peeling of the treated skin, which typically resolve within 1-2 weeks. Some patients experience temporary changes in skin pigmentation, though this usually normalises over time. Rarely, scarring or infection may occur. Following aftercare instructions carefully minimises the risk of complications. Our dermatology team at Prema Health will monitor your progress and is available to address any concerns during your recovery.

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Conditions Treated

Photodynamic Therapy is highly effective for treating actinic keratoses (solar keratoses), which are rough, scaly patches that develop on sun-exposed areas of skin due to years of UV exposure. These pre-cancerous lesions are particularly common on the face, scalp, ears, forearms, and backs of the hands. If left untreated, a small percentage of actinic keratoses can progress to squamous cell carcinoma, a type of skin cancer. PDT provides an excellent treatment option that can address multiple lesions in a single session while achieving superior cosmetic results compared to other destructive methods.

In addition to actinic keratoses, PDT can be used to treat certain cases of superficial basal cell carcinoma, Bowen disease (squamous cell carcinoma in situ), and some inflammatory skin conditions such as severe acne. The treatment is particularly valuable for patients with multiple lesions, those on anticoagulant medications that may complicate surgical procedures, or individuals seeking the best cosmetic outcome. During your consultation at our Dermatology clinic in Portsmouth, our specialist will assess your skin condition and determine whether PDT is the most appropriate treatment option for your needs.

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Our Pillars of Care.

A modern and welcomingenvironment

A modern and welcoming environment

We are proud to deliver a premium patient experience at our state-of-the-art facilities in Hampshire. At Prema, our patients can expect exceptional personal and medical care in a warm and relaxing environment.

Caring and expert staff

Caring and expert staff

Without exception, our patients come first. We take the time to ask the right questions and listen to our patients individual needs, tailoring the perfect patient experience. With compassion and understanding, our patients can be assured that we have their best interests in mind.

Treatment within reasonable time

Treatment in good time

We believe in a collaborative experience for our patients. We work together to deliver exceptional care in a timely fashion. We also understand that sometimes there is a need to be seen swiftly; Prema has the resources to deliver efficient care, effectively.

A modern and welcomingenvironment

A modern and welcoming environment

We are proud to deliver a premium patient experience at our state-of-the-art facilities in Hampshire. At Prema, our patients can expect exceptional personal and medical care in a warm and relaxing environment.

Caring and expert staff

Caring and expert staff

Without exception, our patients come first. We take the time to ask the right questions and listen to our patients individual needs, tailoring the perfect patient experience. With compassion and understanding, our patients can be assured that we have their best interests in mind.

Treatment within reasonable time

Treatment in good time

We believe in a collaborative experience for our patients. We work together to deliver exceptional care in a timely fashion. We also understand that sometimes there is a need to be seen swiftly; Prema has the resources to deliver efficient care, effectively.